Identification of suicide brain transcriptomic signatures using meta-analysis of multiple cohorts.

Transl Psychiatry · 2026 · PMC13039836 · PMID 41916959

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failed to reach statistical significanceno p-value reported

Due to the small number of cohorts, coefficients in meta-regressions generally failed to reach statistical significance in most genes.

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nominally significantno p-value reported

Then, obtained DE genes were further filtered to include only hits that are already nominally significant in GSE144136 or GSE213982 and then were meta-analysed using random-effects model in metafor similar to primary pipeline described in Section 2.8.

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