Tissue-derived extracellular vesicles-mediated delivery of a hepatic enzyme living panorama (HELP) for treating multifactorial liver diseases.

J Nanobiotechnology · 2026 · PMC13049865 · PMID 41761172

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

a clear trendno p-value reported

Specifically, there was a clear trend toward the downregulation of related genes, including Cyp2c9 , Cyp3a4 , Ugt1a1 and Ugt2a1 , in PA-treated cells.

also in 19,460 other papers

did not reach statistical significanceno p-value reported

While trends of elevation were observed, triglyceride (TG) and total cholesterol (TC) did not reach statistical significance in this model (Fig. 5 c-f).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.