Beyond eosinophils: A proteomic dissection of remodeling and inflammation in suspected eosinophilic esophagitis.

J Pediatr Gastroenterol Nutr · 2026 · PMC13050820 · PMID 41536225

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nominally significantno p-value reported

CCL26, a marker of eosinophilic inflammation, was the most significantly upregulated biomarker in EoE, was also elevated in BCH, and remained nominally significant even after adjusting for maximum eosinophil count.

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did not reach statistical significanceno p-value reported

Other markers, including IL5RA, COL9A1, and IL2, showed nominal significance but did not reach statistical significance after multiple testing correction.

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