Cardioprotective Effects of Finerenone Associated With the Suppression of Myocardial Sodium Accumulation in Aldosterone/Salt-Loaded Rats.

J Am Heart Assoc · 2026 · PMC13055678 · PMID 41778591

Europe PMC DOI

hedged sentences

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closest p · 1.0× alpha

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boldest claim

The sentences

did not reach statistical significanceP > 0.05actually significant

Although a numerical decrease in CD68 + CD206 + macrophages was observed in the aldosterone+finerenone group, this did not reach statistical significance ( P > 0.05).

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showed a trendno p-value reported

Additionally, these rats showed a trend toward increased mitral valve deceleration time ( Table ), which is consistent with diastolic dysfunction.

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