Pseudohypoxia induced by iron chelators preserves working memory performance in aged mice.

Sci Rep · 2026 · PMC13056959 · PMID 41772141

Europe PMC DOI

hedged sentences

0.0098

closest p · 0.2× alpha

0.4000

boldest claim

The sentences

a trend toward significancep = 0.0098actually significant

Subsequent non-parametric Steel’s multiple comparisons indicated that SP10 significantly increased the measured values relative to the control group ( p = 0.0098, 95% CI [0.80 to 5.70], Cliff’s delta = 1.0), whereas Roxadustat also showed an elevation with a trend toward significance ( p = 0.0098, 95% CI [0.80 to 3.60], Cliff’s delta = 1.0).

also in 1,755 other papers

marginally significantp = 0.061so close (0.05 < p ≤ 0.1)

Tau pathway For phosphorylated Tau (pTau), the non-parametric Kruskal-Wallis test revealed a marginally significant overall group effect (H = 5.59, p = 0.061).

also in 8,505 other papers

did not reach statistical significancep = 0.200not close (p > 0.1)

Although Steel’s test for SP10 did not reach statistical significance ( p = 0.200), it exhibited a large effect size (Cliff’s delta = 0.78) with a mean difference of 0.49 (95% CI [-0.19 to 1.17]).

also in 53,799 other papers

a negative trendp = 0.400not close (p > 0.1)

Roxadustat showed a negative trend with a medium effect size (Cliff’s delta = -0.56, p = 0.400) and a mean difference of -0.34 (95% CI [-1.02 to 0.34]).

also in 1,819 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.