Re-evaluating DAA therapy in active hepatocellular carcinoma: from controversy to clinical considerations.

J Liver Cancer · 2026 · PMC13062630 · PMID 41327905

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

a strong trendP =0.07so close (0.05 < p ≤ 0.1)

did not reach statistical significanceno p-value reported

34 were neutral overall; in a multivariable analysis after liver transplantation, DAA use did not reach statistical significance for recurrence but showed a strong trend toward higher recurrence risk (HR, 5.17; 95% CI, 0.89-29.81; P =0.07).

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