Cardiovascular outcomes of intensive blood pressure control in patients with and without metabolic dysfunction-associated fatty liver disease: post hoc analysis of the CRHCP trial.

BMC Med · 2026 · PMC13067411 · PMID 41776553

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did not reach statistical significanceno p-value reported

Additionally, the risk of symptomatic hypotension was significantly increased only in patients without MAFLD ( RR , 1.56; 95% CI, 1.07–2.27; P = 0.021; NNH = 37.9); however, the interaction term did not reach statistical significance ( P for interaction = 0.145).

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showed a trendno p-value reported

An exception was observed in participants without baseline antihypertensive treatment, who showed a trend toward benefit without reaching statistical significance.

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