Barely Significant
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Pubertal development and hormonal modulation in pediatric low-grade gliomas: a retrospective cohort study.

J Neurooncol · 2026 · PMC13068672 · PMID 41961358

Europe PMCDOI
3
hedged sentences
0.1000
closest p · 2.0× alpha
0.1000
boldest claim

The sentences

did not reach statistical significancep = 0.10so close (0.05 < p ≤ 0.1)
In the overall comparison, patients treated with a GnRH analogue showed a trend toward longer PFS compared with untreated controls; however, this difference did not reach statistical significance ( p = 0.10).

also in 75,281 other papers

a possible trendno p-value reported
Moreover, in our cohort, hormonal suppression with GnRH analogues in patients with central precocious puberty was associated with a possible trend toward improved progression-free survival (PFS) compared with untreated patients.

also in 939 other papers

showed a trendno p-value reported
Compared with age-matched children without CPP, GnRH therapy showed a trend toward longer PFS, though not statistically significant ( p = 0.10).

also in 33,237 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.