Baseline pain, fatigue, and sleep quality predict 12-week pain improvement in inflammatory arthritis: retrospective real-world analysis of a digital health application cohort.

Rheumatol Int · 2026 · PMC13068763 · PMID 41961305

Europe PMC DOI

hedged sentences

0.0790

closest p · 1.6× alpha

0.1000

boldest claim

The sentences

trend toward significancep = 0.079so close (0.05 < p ≤ 0.1)

Additionally, the number of App Modules Completed showed a stronger trend toward significance (OR 1.67, p = 0.079) than in the whole cohort, suggesting that behavioral engagement and sleep hygiene may be particularly effective drivers of pain relief when systemic inflammation is controlled.

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a positive trendp = 0.100so close (0.05 < p ≤ 0.1)

Diet quality showed a positive trend (Adjusted OR 1.16, 95% CI 0.98 to 1.37, p = 0.100) but did not reach statistical significance in the fully adjusted model.

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did not reach statistical significanceno p-value reported

Diet quality showed a positive trend (Adjusted OR 1.16, 95% CI 0.98 to 1.37, p = 0.100) but did not reach statistical significance in the fully adjusted model.

also in 75,281 other papers

showed a trendno p-value reported

While patients with SpA showed a trend toward better outcomes compared to RA and PsA, our analysis suggests this may be partly mediated by younger age and specific engagement patterns rather than diagnosis alone.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.