3D morphological analysis of age and sex-related changes in human cortical bone remodeling spaces using micro-CT.

J Anat · 2026 · PMC13069156 · PMID 41178035

Europe PMC DOI

hedged sentences

0.0850

closest p · 1.7× alpha

0.0850

boldest claim

The sentences

a decreasing trendp = 0.085so close (0.05 < p ≤ 0.1)

did not reach statistical significancep = 0.085so close (0.05 < p ≤ 0.1)

While maximum radius did not reach statistical significance, it still showed a decreasing trend with increasing age ( r = −0.127; p = 0.085).

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a significant trendno p-value reported

Although canal diameter did not show a significant trend with age in females, it is possible that the longer transition zone is more often accompanied by larger canal diameter in older females, indicating insufficient infilling and a potentially more persistent, systemic and permanent remodeling imbalance, while in younger males, the long transition zone may be a temporary lag in formation initiation that does not compromise bone quality, and will later be sufficiently infilled.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.