Barely Significant
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Clinical predictors of postoperative cerebrospinal fluid leakage following endoscopic endonasal surgery for pituitary neuroendocrine tumors: a retrospective cohort study.

BMC Neurol · 2026 · PMC13069808 · PMID 41787328

2
hedged sentences
0.0680
closest p · 1.4× alpha
0.0680
boldest claim

The sentences

did not reach statistical significanceP = 0.068so close (0.05 < p ≤ 0.1)
ACTH-secreting pathology demonstrated a trend towards association but did not reach statistical significance (OR 4.76; 95% CI 0.89–25.36; P = 0.068).

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showed a trendP = 0.068so close (0.05 < p ≤ 0.1)
In our study, ACTH-secreting adenomas showed a trend towards association with postoperative failure ( OR 4.76; 95% CI 0.89–25.36; P = 0.068), with a leakage rate of 30.0% (3/10 cases) although this did not reach strict statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.