Mitochondrial dysfunction in immune cells during the perioperative period: mechanisms, emerging therapeutic strategies, and implications for multi-organ protection.

A trial of cyclosporine at reperfusion in liver transplant showed a trend to less AST release, though not significant.

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However, due to factors such as the relatively small sample size, this study did not reach statistical significance, and the relevant conclusions still need to be further confirmed by more large - scale multicenter studies ( 194 ).

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