Barely Significant
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Recurring Bleeding Events Requiring Red Blood Cell Transfusion After Left Atrial Appendage Closure Are Associated with Increased Mortality.

J Clin Med · 2026 · PMC13073375 · PMID 41976927

Europe PMCDOI
3
hedged sentences
0.0002
closest p · 0.0× alpha
0.2100
boldest claim

The sentences

highly significantp = 0.00019actually significant
As demonstrated in the table, patients requiring both pre- and postoperative transfusions have a significantly higher risk of mortality compared to those without transfusions (HR = 5.97, p = 0.00019, highly significant).

also in 132,142 other papers

did not reach statistical significancep = 0.21not close (p > 0.1)
Even compared with only preoperative transfusion, adding postoperative transfusion increases risk (HR 2.07), but did not reach statistical significance ( p = 0.21).

also in 111,027 other papers

showed a trendno p-value reported
Preoperative transfusion alone showed a trend toward increased mortality but was not statistically significant ( p = 0.09).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.