Donor selection for patients with HLA-homozygous haplotypes in allogeneic hematopoietic stem cell transplantation.

Ann Hematol · 2026 · PMC13079546 · PMID 41979679

Europe PMC DOI

hedged sentences

0.0610

closest p · 1.2× alpha

0.0970

boldest claim

The sentences

a nonsignificant trendP = 0.061so close (0.05 < p ≤ 0.1)

Compared with the unrelated donor homo-to-homo group, overall survival was inferior in the cord blood homo-to-homo group (adjusted hazard ratio [HR], 1.71; 95% confidence interval [CI], 1.11–2.64; P = 0.015), whereas the unrelated donor hetero-to-homo group showed a nonsignificant trend toward inferior overall survival (adjusted HR, 1.77; 95% CI, 0.97–3.22; P = 0.061).

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showed a trendP = 0.097so close (0.05 < p ≤ 0.1)

In multivariate analysis, the CB group showed a trend toward higher mortality risk compared with the URD group (adjusted hazard ratio [HR], 1.30; 95% confidence interval CI, 0.95–1.77, P = 0.097) (Supplementary Table S2 ).

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did not reach statistical significanceno p-value reported

In contrast, the CB homo-to-homo group was associated with inferior overall survival, whereas the URD hetero-to-homo group showed a trend toward inferior overall survival that did not reach statistical significance.

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