GIPR signaling modulates PYY-induced hypophagia and malaise in rodents.

Mol Metab · 2026 · PMC13080594 · PMID 41679433

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showed a trendno p-value reported

Combinatorial treatment of GIPG013 and LA-PYY also suppressed food intake and body weight compared to controls, but only showed a trend towards enhanced hypoghagic and body weight lowering effects when compared to LA-PYY alone ( Fig. 5 ). 4.

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did not reach statistical significanceno p-value reported

While a trend toward enhanced efficacy was observed, this effect did not reach statistical significance.

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