Systemic therapy outcomes following separation surgery versus maximal feasible resection for spinal metastases from non-small cell lung cancer: a real-world retrospective cohort study.

World J Surg Oncol · 2026 · PMC13088601 · PMID 41808173

Europe PMC DOI

hedged sentences

0.0820

closest p · 1.6× alpha

0.2770

boldest claim

The sentences

showed a trendP = 0.082so close (0.05 < p ≤ 0.1)

Analysis of the BOR showed a trend favoring the MFR group ( P = 0.082).

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a favorable trendP = 0.088so close (0.05 < p ≤ 0.1)

In addition, a favorable trend toward improved OS was observed when comparing MFR plus denosumab with SS plus denosumab (HR = 0.34, 95% CI: 0.10–1.18, P = 0.088), although this did not reach statistical significance (Fig. 2 B).

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did not reach statistical significanceP = 0.277not close (p > 0.1)

The ORR was higher in the MFR group (21.4%) compared to the SS group (4.55%), although the difference did not reach statistical significance ( P = 0.277).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.