Hypothyroidism as Prognostic Factor in Cutaneous Melanoma: A 1553-Patient Single-Center Study.

Cancer Med · 2026 · PMC13093624 · PMID 41845929

Europe PMC DOI

hedged sentences

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

showed a trendp = 0.052so close (0.05 < p ≤ 0.1)

Even when metastases were present, hypothyroid patients had significantly fewer affected nodes ( p = 0.009) and showed a trend toward lower overall lymph node burden ( p = 0.052).

also in 53,322 other papers

did not reach statistical significanceno p-value reported

They also reported a lower frequency of ulcerated melanomas among hypothyroid patients, although, as in our study, this did not reach statistical significance.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.