Barely Significant
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The remnant cholesterol inflammatory index and risk of future cardiovascular disease in early CKM syndrome: findings from CHARLS.

J Health Popul Nutr · 2026 · PMC13093941 · PMID 41814430

2
hedged sentences
0.0430
closest p · 0.9× alpha
0.0430
boldest claim

The sentences

a significant trendP = 0.043actually significant
Nevertheless, a significant trend across RCII quartiles was observed in all models (P for trend < 0.001 for Models 1 and 2; P = 0.043 for Model 3), supporting an overall dose–response pattern.

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In the fully adjusted Model 3, elevated risk persisted for Q2 (HR 1.199; 95% CI 1.000–1.437; P = 0.050) and Q4 (HR 1.239; 95% CI 1.029–1.492; P = 0.024), whereas the association for Q3 was attenuated and did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.