Systemic iron availability differentially shapes tumor and brain iron handling in a sex-dependent manner in glioblastoma.

PLoS One · 2026 · PMC13095122 · PMID 42008565

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hedged sentences

0.0600

closest p · 1.2× alpha

0.0700

boldest claim

The sentences

did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

0.4425 ± 0.9117), although this difference did not reach statistical significance (p = 0.06) ( Fig 3A ).

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failed to reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

High iron female mice also had slightly elevated tumor iron compared to control (15.60 ± 5.757 vs 10.19 ± 3.469 g/tissue weight), though this failed to reach statistical significance (p = 0.07).

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