Effectiveness and Persistence of Long-Acting Injectable Cabotegravir and Rilpivirine in Migrant Individuals Living With HIV in Spain: Substudy of the RELATIVITY Cohort.

In this case, the cumulative incidence of discontinuation was higher in migrants across all categories, including a borderline significant trend towards higher VF (aHR 3.51, 95% CI 0.95–12.98, p = 0.045), but with substantial uncertainty given the small number of failures. 3.4 On‐Label Analysis The results of the secondary analysis, including only PWH in whom the prescription was in accordance with the technical sheet, and excluding those who had NNRTI or INSTI mutations, are presented in File S4, Tables S4.1 − S4.4 and Figure S4 . 4 Discussion In our study, migrant PWH switching to LAI CAB+RPV exhibited low VF rates, comparable to those observed in pivotal clinical trials.

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In the multivariate Cox proportional hazards regression model, migrant status showed a significant trend towards higher VF (aHR 2.16; 95% CI: 0.89–5.22; p = 0.079), limited by the low number of events and imprecise estimates (File S2, Table S2 ). 3.2.2 Factors Associated With VF Among Migrants Table 4 shows the characteristics of patients in the cohort experiencing VF, including emerging RAMs.

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