How nature nurtures: prenatal exposure to green space buffers the effects of maternal stress on neonatal BDNF methylation.

Mol Psychiatry · 2026 · PMC13099633 · PMID 41390788

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significancep = 0.059so close (0.05 < p ≤ 0.1)

The interaction between maternal anxiety and tree cover on newborns’ PC 1 BDNF DNAm was suggestive but did not reach statistical significance ( β = −0.22 [95% CI: .−0.45, −0.01], p = 0.059) and the overall model was also not significant ( p = 0.10).

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approached significancep = 0.060so close (0.05 < p ≤ 0.1)

When using larger buffers (500 and 1000 m), the interaction effects approached significance but did not reach statistical thresholds ( p = 0.060 and p = 0.090, respectively), and the full models were not significant.

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