Total marrow irradiation-based conditioning for allogeneic hematopoietic stem cell transplantation in patients with hematologic malignancies: A multicenter real-world study.

Cell Transplant · 2026 · PMC13100420 · PMID 41995030

Europe PMC DOI

hedged sentences

0.5510

closest p · 11.0× alpha

0.5510

boldest claim

The sentences

showed a trendP = 0.551not close (p > 0.1)

Relapse (20.1% (10.6–29.7) versus 35.2% (24.3–46.1), P = 0.058) showed a trend toward lower incidence in the >9 Gy group, while NRM (12.6% (3.9–21.4) versus 14.4% (7.1–21.6), P = 0.551), GRFS 39.3% (29.0–53.3) versus 35.8% (26.5–48.4), P = 0.458), aGVHD 38.3% (27.0–49.6) versus 22.7% (14.1–31.3), P = 0.030) and cGVHD outcomes were comparable.

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did not reach statistical significanceno p-value reported

Similar trends were observed (2-year OS 72.2% (55.8-93.4) versus 64.8% (51.3–81.8); DFS 61.6% (44.2-85.7) versus 50.7% (37.1–69.2), P = 0.070), although differences did not reach statistical significance.

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