Combined impact of ROR2 and its ligands on the pathogenesis and prognosis of idiopathic pulmonary fibrosis.

Sarcoidosis Vasc Diffuse Lung Dis · 2026 · PMC13101014 · PMID 41891408

Europe PMC DOI

hedged sentences

0.4840

closest p · 9.7× alpha

0.4840

boldest claim

The sentences

did not reach statistical significancep = 0.484not close (p > 0.1)

Although WNT1 and WNT5A levels tended to be higher in the IPF group, these differences did not reach statistical significance ([0.11 (0.03–0.23) ng/mL vs. 0.06 (0.02–0.16) ng/mL, p = 0.484]; [9.00 (0–21.00) ng/mL vs. 1.00 (0–10.00) ng/mL, p = 0.118], respectively) ( Figure 1 ).

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showed a trendno p-value reported

Exploratory stratification based on combined ROR2 and WNT5A expression identified a subgroup with low ROR2 / high WNT5A levels that showed a trend toward better prognosis.

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