Circulating Tumor Cells Detected Using EpAb3-5 as Prognostic Indicators in Head and Neck Squamous Cell Carcinoma.

Analysis according to overall clinical stage showed a trend toward higher EpAb3-5-assessed EpCAM expression in advanced-stage disease (Stage III-IV) compared with early-stage disease (Stage I-II), but this difference did not reach statistical significance (Figure 2 C).

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In early-stage patients, low EpAb3-5-assessed EpCAM expression was significantly associated with improved OS in most early-stage subgroup analyses (Figure 3 A, 3C, and 3D), whereas only a nonsignificant trend was observed in node-negative patients (Figure 3 B).

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