Treatment strategies for small cell carcinoma of the esophagus: comparative analysis of multimodal regimens in two independent real-world cohorts.

Oncologist · 2026 · PMC13105289 · PMID 41912432

Europe PMC DOI

hedged sentences

0.0920

closest p · 1.8× alpha

0.0920

boldest claim

The sentences

did not reach statistical significanceP = .092so close (0.05 < p ≤ 0.1)

Similarly, in the Chinese cohort, although patients with tumors in the lower esophagus or with stage III–IV disease appeared to derive greater benefit from CT + S (HR = 0.466 and 0.585, respectively), these associations did not reach statistical significance ( P = .092 and .072).

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showed a trendno p-value reported

In the Chinese cohort ( Figure 2A ), patients treated with CT + S showed a trend toward better OS compared to those receiving CT + RT, although the difference was not statistically significant (HR = 0.75, 95% CI: 0.514-1.093, P = .134).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.