Survival Outcomes in Lymph Node-Positive Merkel Cell Carcinoma (Stage III): A Comparison Between Known and Unknown Primary Tumors and Their Sun Exposure Sites.

For DFS, both MCCUP status and non-sun-exposed tumor location showed a trend toward improved outcomes; however, these did not reach statistical significance in the multivariable model, consistent with the borderline significance observed in the univariate analysis ( p = 0.050 and p = 0.066, respectively).

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The median DFS was 32 months for non-sun-exposed tumors versus 18.5 months for sun-exposed tumors, demonstrating a trend toward improved DFS that did not reach statistical significance ( p = 0.0663).

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The mean age at diagnosis was comparable between groups but showed a trend toward younger age in the UNPMCC group (67.8 years) compared with patients with known primary MCC (71.2 years).

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