Metabolomic Profiling of Extracellular Vesicles Reveals Distinct Metabolic Dysregulation and Treatment-Specific Signatures in Depression.

Biomolecules · 2026 · PMC13113742 · PMID 42072654

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did not reach statistical significanceno p-value reported

After duloxetine treatment, its levels increased; however, this change did not reach statistical significance after FDR correction.

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nominally significantno p-value reported

For tryptophan and phenylacetylglutamine, the treatment effect was opposite to that observed for leucine, and only nominally significant.

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