RNA-Seq Analysis of Human Cumulus Cells Identifies Angiogenic Pathways Associated with Infertility.

Cells · 2026 · PMC13114718 · PMID 42041545

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showed a trendno p-value reported

In our study, ANGPT1 expression showed a trend toward higher levels in infertile patients, while ANGPT2 was relatively higher in donors.

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did not reach statistical significanceno p-value reported

NRP2 and THBS1 were also downregulated in patients, consistent with the RNA-seq results, though these differences did not reach statistical significance in the qPCR cohort.

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