Barely Significant
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Real-World Outcomes of Palbociclib with Endocrine Therapy in HR+/HER2- Metastatic Breast Cancer: A Retrospective Study from Saudi Arabia.

Cancers (Basel) · 2026 · PMC13115174 · PMID 42073594

2
hedged sentences
0.0500
closest p · 1.0× alpha
0.0500
boldest claim

The sentences

did not reach statistical significancep > 0.05actually significant
Other variables, including BMI, cancer type, endocrine therapy, family history of cancer, BRCA mutation status, and line of therapy ( Table 5 ), did not reach statistical significance ( p > 0.05), although trends were observed.

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showed a trendno p-value reported
For instance, patients on an SERD (fulvestrant) showed a higher hazard ratio (HR = 2.302, p = 0.0678), and those with non-visceral metastases (HR = 2.008, p = 0.0696) also showed a trend toward poorer outcomes without statistical significance. 3.4.

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