Prognostic Significance of Selected Tumor Stroma Parameters in Patients with HER2-Positive Breast Cancer Treated with Adjuvant Trastuzumab.

Cancers (Basel) · 2026 · PMC13115492 · PMID 42073567

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0650

boldest claim

The sentences

borderline significantp = 0.054so close (0.05 < p ≤ 0.1)

A central area of fibrosis/hyalinization was less frequently detected in G3 tumors, although this finding was borderline significant ( p = 0.054).

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did not reach statistical significancep = 0.065so close (0.05 < p ≤ 0.1)

There was a trend toward more frequent eosinophil presence in tumors that did not metastasize to regional lymph nodes; however, this association did not reach statistical significance ( p = 0.065 and p = 0.063).

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a borderline significant trendno p-value reported

In the present study, no significant relationship was found between the basic clinical and pathological parameters and the presence of central fibrosis/hyalinization area, except for a borderline significant trend toward less frequent occurrence in higher-grade tumors.

also in 64 other papers

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