Platelet-Activating Factor Pathway in Women With Metabolic Dysfunction-Associated Steatotic Liver Disease and Obesity.

Although PAFR expression did not reach statistical significance in either model, it showed a clear trend toward association with both MASLD (OR = 9.85, p = 0.197) and MASH (OR = 2.83, p = 0.068), supporting its potential role in disease progression (Table 2 ). 3.3 Hepatic Relative mRNA Expression of PAFR in Relation to Histological Features To further investigate the relationship between hepatic PAFR expression and histological characteristics of MASLD, we analyzed its expression across different grades of steatosis, lobular inflammation, hepatocellular ballooning, and NAS (Figure 3A ).

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