Comparative Predictive Value of First-Trimester Crown-Rump Length and Nuchal Translucency Discordance for Fetal Growth Restriction in Twin Pregnancies: A Retrospective Cohort Study.

For NT discordance, a nominally significant interaction term was identified ( p = 0.020); however, this result should be interpreted with caution given the small number of NT-positive MCDA cases ( n = 3) and model non-convergence, precluding reliable subgroup-specific estimates.

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In contrast, the NT discordance modelled as a continuous variable did not reach statistical significance (OR per 1% increase = 1.02, 95% CI 0.99–1.05), further supporting the superior predictive value of CRL discordance.

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