Effects of Two Different Training Programs on Cardiometabolic Health, Body Composition and Irisin in Middle Age Obese Males: A Pilot Study.

A similar pattern was observed for salivary irisin, where a near-significant group × time interaction emerged ( p = 0.051, F(1,10) = 3.868, ηp 2 = 0.279), with increases observed only in the THR group (0.96 ± 0.69 vs. 2.19 ± 2.52 ng/mL, ES = 0.67, moderate-to-large), despite non-significant post hoc comparisons ( p = 0.161) ( Figure 2 , panels A and B).

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9.8 ± 6.9 ng/mL, ES = 1.05, large), although post hoc analysis did not reach statistical significance ( p = 0.106).

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