Combined diagnostic value of NT-proBNP, DLK-1, PSP-D and PCSK-9 in heart failure with preserved ejection fraction: a prospective biomarker study.

Front Cardiovasc Med · 2026 · PMC13121242 · PMID 42058485

Europe PMC DOI

hedged sentences

0.0780

closest p · 1.6× alpha

0.0780

boldest claim

The sentences

of marginal significanceP = 0.078so close (0.05 < p ≤ 0.1)

The difference in PCSK-9 was of marginal significance ( P = 0.078), as detailed in Table 4 . 3.5.

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did not reach statistical significanceno p-value reported

However, the observed elevation did not reach statistical significance, potentially because patients were in the early stages of heart failure at the time of testing.

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