Peritoneal dialysis-induced senescence contributes to treatment failure in long-term PD.

However, the difference did not reach statistical significance.

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LaminB1 showed a decreasing trend in PD samples compared to uremic samples and healthy controls.

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While it was difficult to identify single cells with reliable loss of laminB1, systematic semi-quantitative analysis revealed a clear trend in reduced staining, when comparing biopsy samples of patients with a PD vintage > 12 months to the other groups (Fig. 3 b).

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