Integrated analysis identifies CCNA2 as a candidate diagnostic and prognostic biomarker in oral tongue squamous cell carcinoma.

J Appl Oral Sci · 2026 · PMC13123793 · PMID 41779475

Europe PMC DOI

hedged sentences

0.3600

closest p · 7.2× alpha

0.3600

boldest claim

The sentences

did not reach statistical significancep=0.36not close (p > 0.1)

While CCNA2 protein levels showed prognostic relevance for OS (AUC=0.69, p=0.01), the mRNA-based prediction did not reach statistical significance (AUC=0.63, p=0.36).

also in 111,027 other papers

showed a trendno p-value reported

CCNA2 mRNA levels showed a trend towards association with OS, but the result did not reach statistical significance (AUC =0.63, 95% CI: 0.35–0.91, p= 0.36, Figure 3E ).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.