Barely Significant
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KRAS<sup>G12C</sup> inhibitors versus chemotherapy alone for KRAS<sup>G12C</sup>-mutated non-small cell lung cancer: a pooled analysis of CodeBreaK 200 and KRYSTAL-12 trials.

Front Oncol · 2026 · PMC13124570 · PMID 42063697

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The sentences

a strong trendno p-value reported
did not reach statistical significanceno p-value reported
Although CNS-specific ORR, CR, and PR did not reach statistical significance, the data showed a strong trend favoring KGIs and a significant reduction in CNS progression as the best response.

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