Barely Significant
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Synovial Biomarker Modulation and Clinical Response to Umbilical Cord-Derived MSC Treatment in Knee Osteoarthritis: A Case Series Study.

Cartilage · 2026 · PMC13132980 · PMID 42060495

3
hedged sentences
0.1100
closest p · 2.2× alpha
0.1100
boldest claim

The sentences

not quite statistically significantP = 0.11not close (p > 0.1)
The levels of monocyte chemoattractant protein 1, CCL2, were, on the contrary, readily detectable and showed a median decrease post-treatment, although not quite statistically significant ( P = 0.11) ( Fig. 3B ) .

also in 341 other papers

showed a trendno p-value reported
Measurement of adiponectin showed a trend for increase after treatment; however, the difference was not significant ( P = 0.146).

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The median levels of CD163, a marker of type 2, anti-inflammatory macrophage polarization, increased numerically post-treatment with a P -value of 0.068; therefore, the change did not reach statistical significance ( Fig. 3C ) .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.