The levels of monocyte chemoattractant protein 1, CCL2, were, on the contrary, readily detectable and showed a median decrease post-treatment, although not quite statistically significant ( P = 0.11) ( Fig. 3B ) .
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Synovial Biomarker Modulation and Clinical Response to Umbilical Cord-Derived MSC Treatment in Knee Osteoarthritis: A Case Series Study.
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Measurement of adiponectin showed a trend for increase after treatment; however, the difference was not significant ( P = 0.146).
The median levels of CD163, a marker of type 2, anti-inflammatory macrophage polarization, increased numerically post-treatment with a P -value of 0.068; therefore, the change did not reach statistical significance ( Fig. 3C ) .