Salivary immune alteration persists after caries treatment.

256), the difference did not reach statistical significance ( p > 0.05) (Fig. 5 A).

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Following treatment intervention, immune pathways showed a clear trend toward normalization, reflecting the restoration of salivary balance.

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In the analyzed samples, MUC7 was significantly reduced, whereas MUC5B showed only a decreasing trend, suggesting that MUC7 may be more susceptible to proteolytic degradation.

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