Stromal hypoxia and autophagy signatures as indicators of pathologic response in triple-negative breast cancer.

BMC Cancer · 2026 · PMC13134092 · PMID 41826879

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0830

boldest claim

The sentences

did not reach statistical significancep = 0.070so close (0.05 < p ≤ 0.1)

Although Beclin-1 scores tended to be higher in MP5 tumors, this difference did not reach statistical significance, likely due to limited case numbers ( p = 0.070).

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near-significantp = 0.083so close (0.05 < p ≤ 0.1)

Similarly, HIF-1α (H-Score 1, cut-off = 1.5) demonstrated near-significant association with MP scores ( p = 0.083), where higher HIF-1α levels were more frequently observed in cases with complete or good response.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.