Risk Factors for Severe Postoperative Complications After Laparoscopic Colorectal Cancer Surgery in Octogenarians: A Retrospective Cohort Study.

Hemoglobin <120 g/L (OR = 2.56, 95% CI: 0.99–6.60, P = 0.05) and ASA III (OR = 2.49, 95% CI: 0.98–6.35, P = 0.06) showed borderline significance.

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Preoperative anemia, reflected by hemoglobin <120 g/L, also showed a trend toward increased risk, consistent with evidence linking anemia to impaired wound healing and increased infection risk. 22 Although preoperative anemia is routinely evaluated and corrected when appropriate in our center, full optimization is not always feasible in elderly patients requiring timely colorectal cancer surgery.

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Rectal cancer also showed a trend toward a higher risk of severe postoperative complications compared with colonic cancer (OR 2.11), although this association did not reach statistical significance, likely due to the limited number of events and the inherent complexity of pelvic surgery in elderly patients.

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