Risk prediction and surgical decision-making for pathological fractures in phalangeal enchondroma: validation of the 0.51 threshold and outcome comparison of prophylactic intervention in 65 patients.

It is notable that the difference in mean ratios between the two groups did not reach statistical significance in the univariate analysis [ 6 ]; this seemingly paradoxical finding, in fact, unveils the pathological mechanism of “occult microfracture.” Patients in the Non-fracture Group with a ratio > 0.51 universally presented with preoperative pain, a finding that strongly corroborates the report by Ha et al., which noted a 100% prevalence of pain in patients with pathological fractures.

also in 111,027 other papers

Multivariate analysis demonstrated a strong trend suggesting that a higher ratio is associated with increased fracture risk (OR = 8.81), although statistical significance was likely limited by sample size.

also in 5,725 other papers