RMC-6272, a selective third-generation bi-steric mTORC1 inhibitor, improves cardiac function in pressure overload-induced cardiac hypertrophy.

J Mol Cell Cardiol Plus · 2026 · PMC13136768 · PMID 42088305

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

While RMC-6272 treatment showed a trend toward reduced heart weight-to-body weight ratios, the reduction did not reach statistical significance ( Fig. 5 E).

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