Drug-Coated Balloon (Optilume<sup>®</sup>) Shows a Low Reintervention Rate in Patients With Bulbar Urethral Strictures: Real-World Data From Two German Centers.

Although there was a trend toward better outcomes in treatment‐naïve patients, the difference did not reach statistical significance, possibly due to the limited sample size.

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Conclusions Optilume demonstrated excellent mid‐term outcomes (median follow‐up: 29.5 months) in the treatment of bulbar urethral strictures, with significant improvements in symptom burden and QoL and a low reintervention rate (2.5%) in a real‐world two‐center cohort with a nonsignificant trend toward greater symptomatic improvement in treatment‐naïve individuals.

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Treatment‐naïve patients showed a trend toward better outcomes.

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