E2F3 activates NF-κB signaling through TRIM26 mediated TAB1 ubiquitination in pancreatic cancer.

While E2F3 did not reach statistical significance (HR = 1.347, p = 0.185), its elevated hazard ratio suggests a potential role in disease progression, potentially masked by overlapping effects with other clinical variables.

also in 111,027 other papers

This again yielded a short list that included TRIM26 supporting the robustness of our screen (Figure 5 L), Clinically, high TRIM26 expression associated with shorter disease specific survival in PDAC (HR = 1.75, p = 0.020; Figure 5 M), and showed a trend toward worse overall survival that did not reach statistical significance ( Figure S4 G).

also in 53,322 other papers