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Characterization of isavuconazole pharmacokinetics and pharmacodynamics in a real-life cohort.

JAC Antimicrob Resist · 2026 · PMC13138873 · PMID 42088097

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showed a trendno p-value reported
Although our PK-PD analysis showed a trend for an association between C min or AUC and outcomes, further prospective investigations in properly sized cohorts remain warranted to confirm these results.

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A trend was observed between C min or AUC and the probability of treatment success, but did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.