Impact of Pharmacokinetic Gene Polymorphisms on Statin-Induced Myotoxicity in Thai Patients Treated With Simvastatin.

Clin Transl Sci · 2026 · PMC13140828 · PMID 41860236

Europe PMC DOI

hedged sentences

0.2000

closest p · 4.0× alpha

0.2000

boldest claim

The sentences

did not reach statistical significancep = 0.20not close (p > 0.1)

15.2%), but this difference did not reach statistical significance ( p = 0.20).

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showed a trendno p-value reported

Additionally, the SLCO1B1 rs2306283 (c.388A>G) G allele showed a trend toward association with SIM, although it did not reach statistical significance ( p = 0.08).

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