Daltroban showed a parallel reduction in both brain microthrombi count and DND compared with vehicle, although the reductions did not reach statistical significance (microthrombi, P = 0.086; DND, P = 0.159).
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Platelets cause microvascular occlusion and delayed neurological deficits after subarachnoid hemorrhage in mice.
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0.0860
0.1590
The sentences
a strong trendP < 0.159
Although daltroban showed a strong trend toward DND reduction ( P < 0.159 compared with vehicle) with reduced brain microthrombi formation, WEB2086 did not lower DND incidence or microthrombi.