Barely Significant
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Impact of carcinoma <i>in situ</i> of bladder at transurethral resection and radical cystectomy on survival: Retrospective multicenter study.

Investig Clin Urol · 2026 · PMC13145770 · PMID 42065660

Europe PMCDOI
2
hedged sentences
0.0900
closest p · 1.8× alpha
0.0900
boldest claim

The sentences

did not reach statistical significancep=0.09so close (0.05 < p ≤ 0.1)
In another study with 410 patients with non-metastatic BC who were treated with RC, concomitant CIS in pure urothelial carcinoma was significantly associated with poor RFS (HR 2.1, 95% CI 1.19–3.58, p=0.01), while the association with CSS did not reach statistical significance (HR 1.7, 95% CI 0.92–3.00, p=0.09) [ 18 ].

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showed a trendno p-value reported
Although neither of the two U.S.-based studies demonstrated statistical significance, both showed a trend toward longer RFS in patients with CIS at TURB compared with those without.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.