Total enteral vs. parenteral nutrition in severe acute pancreatitis: an updated systematic review and GRADE-assessed meta-analysis.

BMC Nutr · 2026 · PMC13147863 · PMID 42087204

Europe PMC DOI

hedged sentences

0.5900

closest p · 11.8× alpha

0.5900

boldest claim

The sentences

did not reach statistical significancep = 0.59not close (p > 0.1)

While the pooled SMD favored TEN, it did not reach statistical significance (MD = 1.18; 95% CI: −3.13 to 5.50; p = 0.59), with high heterogeneity across studies (I2 = 98%).

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showed a trendno p-value reported

TEN was associated with significantly lower risks of infection, multiple organ failure, and mortality, and showed a trend toward reduced need for surgical intervention.

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